Arteta refused to give anything away regarding his goalkeeping selection for the derby, but Aaron Ramsdale has kept two clean sheets in two Premier League games for the Gunners and should retain his place over Bernd Leno.
It is no surprise to see Arsenal's upturn in defensive fortunes coincide with Arteta having his first-choice backline available, as Tierney joins Gabriel Magalhaes, Ben White and Takehiro Tomiyasu in the rearguard.
Bukayo Saka and Emile Smith Rowe will continue to provide support from the flanks, with Nicolas Pepe set to drop out of the side and Eddie Nketiah unlikely to be considered despite his cheeky flick against AFC Wimbledon.
Alexandre Lacazette boasts four goals from his last six North London derbies in the Premier League, but the Frenchman is struggling to displace Pierre-Emerick Aubameyang up top, and that trend is set to continue here.
Arsenal possible starting lineup: Ramsdale; Tomiyasu, White, Gabriel, Tierney; Xhaka, Partey, Odegaard; Saka, Aubameyang, Smith Rowe