Mikel Arteta is expected to take a cautious approach when it comes to the fitness of Bukayo Saka and Emile Smith Rowe for Sunday's Premier League clash with Fulham.
The Gunners are aiming to pick up a third win in a row in all competitions to continue their good run of form heading into the final stretch of the season.
Saka and Smith Rowe passed fitness tests to start Thursday's 4-0 win over Slavia Prague, with the young pair linking up brilliantly alongside Nicolas Pepe in attacking midfield.
However, with this London derby coming just three days on from the trip to the Czech capital, both players could be left out of the side this weekend.
Willian is an obvious replacement on the right, while Gabriel Martinelli will be eager to start on the other side, or possibly through the middle if Alexandre Lacazette is rested.
Arteta has the option of playing Dani Ceballos in a more advanced position and bringing in Mohamed Elneny alongside Thomas Partey, who is slowly growing in stature.
Martin Odegaard is another who can play in that central attacking midfield position, but he has missed three games through injury and is not likely to start this one.
Kieran Tierney and David Luiz are both definitely out, but Arsenal have not missed the pair thanks to good displays from Granit Xhaka, Pablo Mari and Rob Holding at the back.
How Arsenal could line up against Fulham: Leno; Bellerin, Holding, Mari, Xhaka; Partey, Elneny; Willian, Ceballos, Martinelli; Lacazette
> Click here to see how Fulham could line up for this contest
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