However, the club's top goalscorer will return to the attack at Selhurst Park, resulting in his understudy dropping down to the substitutes' bench.
A third alteration remains a possibility with Tyrone Mings picking up a knock during the closing stages against the Toffees.
While Smith has backed the centre-back to shake off the issue before kickoff at the weekend, Kortney Hause will be considered for a recall.
Jack Grealish provided Villa with a welcome boost earlier this week with a 19-minute outing as a substitute, his first appearance since the middle of February.
Despite Villa's lack of goals during his absence, Smith is unlikely to consider his key man for a starting role in London.
Aston Villa possible starting XI: Martinez; Elmohamady, Konsa, Mings, Targett; McGinn, Luiz; Traore, Barkley, El Ghazi; Watkins
Watch the Sports Mole Football Shorts prediction for this game below:
Click here to see how Palace could line up for this fixture body check tags ::