Villarreal vs. Osasuna (Sunday, 1.00pm)
We say: Villarreal 1-0 Osasuna
Osasuna have had longer to prepare for this contest, but Villarreal should be in a confident mood following an impressive run of form. There could be a Europa League hangover for the Yellow Submarine, who will have one eye on next week's last-eight second leg. Emery's side should have enough to triumph this weekend, though, and we fancy a low-scoring game at Estadio de la Ceramica.
Valencia vs. Real Sociedad (Sunday, 3.15pm)
Both Valencia and Real Sociedad will be looking to return to winning ways in La Liga when they continue their respective campaigns with a clash at Mestalla on Sunday afternoon.
Valencia, who lost at Cadiz last weekend, are currently 12th in Spain's top flight, while Real Sociedad occupy fifth position in the table but are level on points with seventh-placed Villarreal.
We say: Valencia 1-1 Real Sociedad
For all of Valencia's problems this season, they are still a side full of talent, and it would not be a surprise to see them triumph on Sunday. Injury-hit Real Sociedad are in need of the points as they battle to keep hold of fifth, though, and we can see the two teams playing out a low-scoring draw at Mestalla.
Real Valladolid vs. Granada (Sunday, 5.30pm)
The visitors are currently ninth in the table, one point behind eighth-placed Celta Vigo, while struggling Valladolid occupy 16th position, just three points clear of the relegation zone.
We say: Real Valladolid 1-1 Granada
Both teams will be desperate to put three points on the board this weekend; it is a bigger game for Valladolid taking everything into consideration, but Granada's recent form is worrying. The pair played out a 1-1 draw when they last locked horns at Estadio Municipal Jose Zorrilla in September 2019, and we can see the same result occurring on Sunday.
Real Betis vs. Atletico (Sunday, 8.00pm)
Atletico, who lost 1-0 at Sevilla last weekend, are currently top of the table, one point clear of second-placed Barcelona, while in-form Betis occupy sixth position in Spain's top flight.
We say: Real Betis 1-1 Atletico Madrid
This is an incredibly difficult game for Atletico, who will not be at full strength on Sunday. Simeone's side might have been knocked off the top of the table by the time that they take to the field for this match, but we are struggling to back them with any real confidence and have therefore settled on a low-scoring draw.