Belgium, top of the world rankings, and holders Portugal go head-to-head on Sunday looking to secure a Euro 2020 quarter-final place against Italy.
Holland, meanwhile, face the Czech Republic at the Puskas Arena for the right to meet Denmark, who ended Wales' hopes with a 4-0 win in Amsterdam on Saturday.
Kasper Dolberg struck either side of half-time at the Johan Cruyff Arena, before late goals from Joakim Maehle and Martin Braithwaite wrapped up an impressive win.
Italy continue to break new ground at Euro 2020. As well as extending their unbeaten run through 31 games to set a new national record, the Azzurri had also not conceded a goal for 1168 minutes until Kalajdzic finally breached their resolute defences. Before that, Holland were the last team to score against Italy in a Nations League fixture during October 2020.
Up next
Holland v Czech Republic (Round of 16, June 27, Budapest, 1700 BST)
Belgium v Portugal (Round of 16, June 27, Seville, 2000)