Martin Montoya, Gerard Pique and Javier Mascherano will all start in defence for Barcelona in tonight's Copa del Rey final against Athletic Bilbao at the Vicente Calderon in Madrid.
The match is coach Pep Guardiola's final game in charge of the team following four highly successful years with the club.
Dani Alves and Carles Puyol are both out injured for the Catalan club, while Eric Abidal recently announced his retirement following liver transplant surgery.
Jose Pinto continues his run in the competition in goal in place of Victor Valdes.
Meanwhile, Bilbao make two changes to the side that lost the Europa League final to Atletico Madrid as Borja Ekiza and Ibai Gomez both start.
Athletic Bilbao: Iraizoz; Iraola, Ekkiza, Amorebieta, Aurtenetxe; De Marcos, Javi Martinez, Ibai; Susaeta, Llorente, Muniain
Subs: Raul, Toquero, San Jose, Gabilondo, Inigo Perez, Gurpegi, Ander Herrera
Barcelona: Pinto; Montoya, Pique, Mascherano, Adriano; Busquets, Xavi, Iniesta; Pedro, Alexis, Messi
Subs: Valdes, Bartra, Thiago, Keita, Afellay, Fabregas, Tello