Villarreal vs. Espanyol (Sunday, 1.00pm)
Villarreal will be bidding to continue their impressive run of form in Spain's top flight when they welcome Espanyol to Estadio de la Ceramica on Sunday afternoon.
The Yellow Submarine, who are sixth in the table, recorded a 4-1 win over Granada last weekend, while Espanyol held title-challenging Sevilla to a 1-1 draw, which has left them in 14th.
We say: Villarreal 2-1 Espanyol
Villarreal's confidence will have grown with their performance against Juventus during the week, and the home side are the strong favourites to pick up three points here. Espanyol have held Barcelona and Sevilla in their last two home games, but we are expecting them to lose this match 2-1.
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Sevilla vs. Real Betis (Sunday, 3.15pm)
One of the biggest fixtures on the La Liga calendar will take place at Estadio Ramon on Sunday afternoon, as Sevilla welcome Real Betis for the Seville derby.
Sevilla are currently second in the table, six points behind league leaders Real Madrid, while Real Betis occupy third, five points below their opponents this weekend.
We say: Sevilla 1-1 Real Betis
Sevilla will be a missing a whole host of important players for this weekend's match, which is certainly a concern considering Real Betis' form entering the contest. With a full squad, we would be backing Sevilla to edge this match, but under the circumstances, Real Betis should be able to claim a welcome point.
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Real Sociedad vs. Osasuna (Sunday, 5.30pm)
After suffering a 4-0 thrashing last weekend, Real Sociedad will look to reclaim a place in the top six of the La Liga table on Sunday, when they play host to Osasuna.
Imanol Alguacil's side have now dropped to seventh spot, while their visitors sit 10th after a defeat of their own last time out.
We say: Real Sociedad 2-1 Osasuna
With two sides keen to bounce back from disappointing defeats, this should be a cagey encounter, and we back the hosts to scrape over the line.
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Barcelona vs. Athletic Bilbao (Sunday, 8.00pm)
Barcelona will be looking to stretch their unbeaten run of form in La Liga to 10 matches when they welcome Athletic Bilbao to Camp Nou on Sunday night.
The Catalan giants are currently fourth in the table, 15 points behind division leaders Real Madrid, while Athletic occupy eighth, two points behind sixth-placed Villarreal heading into the next set of fixtures.
We say: Barcelona 2-1 Athletic Bilbao
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> How Barcelona could line up alongside Athletic Bilbao
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