Atletico vs. Mallorca (Wednesday, 6.30pm)
Atletico Madrid welcome Mallorca to the Spanish capital for a La Liga clash at the Metropolitano on Wednesday.
Diego Simeone's side look set to secure qualification for next season's Champions League despite defeat last time out.
We say: Atletico Madrid 1-1 Mallorca
Mallorca come into the fixture with confidence having won consecutive games, and their fine record versus Atletico should give encouragement.
Atletico will be the favourites but they have flattered to deceive on many occasions this season, and with the season winding down without much to play for, this could be an awkward tie for them.
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Getafe vs. Almeria (Wednesday, 6.30pm)
Getafe and Almeria will meet for a huge relegation six-pointer in La Liga at the Coliseum Alfonso Perez on Wednesday.
The two clubs sit 16th and 17th heading into the midweek round of fixtures, with both in stuttering form.
We say: Getafe 1-0 Almeria
Almeria's woeful away record is clear for all to see, and they may come unstuck again against a side who have been strong at home.
Getafe have not been beaten here since January and will hope to continue an excellent head-to-head record over Almeria.
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Celta Vigo vs. Elche (Wednesday, 9.00pm)
Celta Vigo will aim to heap more misery on La Liga basement dwellers Elche when the two sides face off at Abanca-Balaidos on Wednesday night.
Having won just two of their 30 league matches this season, Elche find themselves 15 points adrift at the foot of the table – 23 points behind 13th-placed Celta.
We say: Celta Vigo 2-0 Elche
We expect Celta Vigo to return to winning ways with a straightforward victory over Elche, who are on course to suffer a sixth successive defeat as their top-flight status continues to slip away.
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Rayo Vallecano vs. Barcelona (Wednesday, 9.00pm)
La Liga leaders Barcelona will be looking to extend their unbeaten top-flight run to eight matches when they travel to the Estadio de Vallecano to face Rayo Vallecano on Wednesday night.
The visitors, meanwhile, are seeking to return to winning ways as they bid to stay in the mix to secure a place in Europe for next season.
We say: Rayo Vallecano 1-2 Barcelona
There has been little to separate the two teams in recent meetings, with Rayo Vallecano coming away as the happier side in each of the last three encounters, and they will be confident of causing another upset on Wednesday in front of their home supporters.
However, with champions-elect Barca keen to get the job done at the summit, we expect Xavi's men to edge a closely-fought contest in the Spanish capital.
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> How Barcelona could line up against Rayo Vallecano
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