Pep Guardiola has made three changes to the side that beat Bayer Leverkusen in midweek for tonight's La Liga encounter with Valencia.
Martin Montoya and Gerard Pique come into defence for the Catalan side in place of Javier Mascherano and the suspended Dabi Alves.
Meanwhile, Pedro is selected in attack ahead of Adriano.
Barca are looking to close Madrid's lead at the top of the league to 10 points.
Barcelona:
Valdes; Abidal, Montoya, Puyol, Pique; Busquets, Fabregas, Iniesta; Alexis, Messi, Pedro
Subs: Pinto, Xavi, Thiago, Adriano, Cuenca, Bartra, Tello
Valencia:
Diego Alves; Miguel, Rami, VĂctor Ruiz, Mathieu; Albelda, Tino Costa; Feghouli, Jonas, Piatti; Soldado
Subs: Topal, Aduriz, Guaita, Pablo Hernandez, Ricardo Costa, Bernat, Jordi Alba