Blackpool caretaker manager Steve Thompson has stuck with the side that beat Wolverhampton Wanderers last weekend.
Stephen Crainey, Angel Martinez and Matt Phillips all maintain their places in the starting lineup.
David Flitcroft hands a Barnsley debut to Rory Delap, who joined the club on deadline day on loan from Stoke City.
The Tykes are without 18-year-old defender John Stones after he joined Everton on Thursday.
Blackpool: Gilks, Baptiste, Broadfoot, Cathcart, Crainey, Angel, Basham, Gomes, Phillips, Ince, Taylor-Fletcher
Barnsley: Steele, Golbourne, Delap, Foster, O'Brien, Perkins, Dagnall, Harewood, Etuhu, Cranie, Kennedy