Bolton Wanderers manager Dougie Freedman will be eager to see an immediate response from his side after they were comfortably beaten by Nottingham Forest last week.
The Trotters fell to a 3-0 defeat at the City Ground, leaving them in 19th position in the Championship table.
Freedman will be without the suspended Darren Pratley, but he could recall striker Jermaine Beckford.
Queens Park Rangers arrive at the Reebok Stadium having picked up seven points from their opening three games.
Boss Harry Redknapp is unlikely to make many changes to the side that beat Ipswich Town last weekend, although Gary O'Neil could be introduced in midfield.
Recent form
Bolton Wanderers: DWDL
Queens Park Rangers: WWDW
Possible starting lineups
Bolton Wanderers: Bogdan; Knight, Baptiste, Tierney, Wheater; Spearing, Hall, Lee, Medo, Moritz; Beckford
Queens Park Rangers: Green; Simpson, Dunne, Hill, Onuoha; Wright-Phillips, Barton, Henry, O'Neil; Austin, Zamora
Sports Mole says: 1-2