Ashley Cole scored his first goal in England in more than six years but Derby were knocked out of the FA Cup after Brighton held on to secure a 2-1 fifth round victory.
The distinguished left-back and seven-time winner of the competition linked up with former Chelsea and England team-mate and now Rams manager Frank Lampard last month, and he managed to get on the score-sheet in only his second appearance for his new club.
Cole, on as a second-half substitute as he continues to build his match fitness, headed home in the 81st minute to score for the first time in his homeland since September 2012.
But it was ultimately in vain as Anthony Knockaert's opener after 33 minutes and Jurgen Locadia's strike in added-on time in the first half secured Brighton's place in the quarter-finals for the second successive season.
Murray Wallace's header after only five minutes proved the difference as Millwall claimed a hard-fought 1-0 victory at AFC Wimbledon.
The League One side had shocked Premier League West Ham in the last round but they were unable to spring another upset as the Lions moved into the quarter-finals for the second time in three seasons.
