Brighton & Hove Albion manager Oscar Garcia has made two changes to the side that ended Leicester City's 21-game unbeaten run on Tuesday.
Casper Ankergren replaces Tomasz Kuszczak in goal, while Bruno comes in for Inigo Calderon.
Charlton Athletic, meanwhile, bring in Lawrie Wilson for Richard Wood following their 3-2 win over Yeovil Town in midweek.
The Seagulls are currently seventh in the league and are chasing the playoffs.
Charlton lie in 21st and need a win to boost their survival hopes.
Brighton & Hove Albion: Ankergren; Bruno, Upson, Greer, Ward; Andrews, Stephens, March; LuaLua, Lingard, Ulloa
Charlton Athletic: Hamer; Wilson, Wiggins, Morrison, Dervite; Poyet, Cousins, Jackson, Ajdarevic; Sordell, Ghoochannejhad