A pitch inspection will take place at Hillsborough at 10.30am following bad weather overnight.
Sheffield Wednesday are scheduled to take on Charlton Athletic in the FA Cup fifth round, but the fixture is now at risk of being called off.
Charlton have stated that the outcome of the inspection will be announced on their official website and social media channels.
Wednesday beat Rochdale in round four, while Charlton knocked out Huddersfield Town.