Cairney has an issue with his knee and could be joined on the sidelines by Aleksandar Mitrovic, who had a slight problem against QPR on Saturday but has since returned to training.
James is back in training after a thigh injury, while Christensen has shaken off a knee complaint.
N'Golo Kante is set to return to training after a hamstring problem but will still miss the Fulham match through suspension.
Fulham provisional squad: Areola, Aina, Andersen, Adarabioyo, Tete, Decordova-Reid, Reed, Anguissa, Lookman, Robinson, Cavaleiro, Rodak, Ream, Kebano, Bryan, Onomah, Kongolo, Kamara, Hector.
Chelsea provisional squad: Mendy, James, Silva, Zouma, Chilwell, Kovacic, Jorginho, Mount, Ziyech, Werner, Pulisic, Arrizabalaga, Azpilicueta, Rudiger, Christensen, Gilmour, Havertz, Hudson-Odoi, Giroud, Abraham.