Sharp came close to a second for Doncaster minutes later, but he saw his header saved by Alex McCarthy.
Le Fondre stepped up to take the resulting penalty and slotted his effort past Sam Johnstone.
They were close to scoring again soon after, but Le Fondre fired over from Garath McCleary's cross.
With four minutes left to play, the visitors took the lead when Pogrebnyak headed Jake Taylor's cross into the roof of the net from close range.
Pogrebnyak made sure of the points when he slotted in from Pearce's pass in stoppage time, as the Royals moved up to fifth in the table. body check tags ::