Steven Gerrard and Kyle Walker have been ruled out of England's friendly against Chile on Friday through injury.
The pair did not take part in training with the rest of the squad at London Colney on Wednesday to work separately in the gym.
Both players will now sit out the match against the South Americans at Wembley Stadium.
Daniel Sturridge joined the duo away from the other players, though he is expected to be fit to play.
Manager Roy Hodgson has also confirmed that Frank Lampard is suffering with a cold, but the midfielder is unlikely to miss the game.