On the same day that Sam Allardyce was given the shove, PSV have confirmed that Brands will take up the position at Goodison Park from this summer.
A statement from Brands read: "It's really hard to let go of something that's good, but I'm going to do that anyway. In my job, too, the Premier League is of course a great thing.
"It is the biggest competition in the world in all respects. I now get the chance to do something in my own way. I am really looking forward to that."
Brands departs the Dutch club on the back of their third Eredivisie title success in four seasons.