A cross from Freek Heerkens provided Wuytens for his first Willem goal since joining on a free transfer in the summer on 21 minutes.
While possession was shared fairly equally, Jurgen Streppel's side dominated in terms of chances, but had to wait until after the break to extend their lead.
Armenteros raced on to a Robbie Haemhouts through pass on 56 minutes to double Willem's advantage, and they effectively secured the points when the striker put them three up on 74 minutes.
Tannane linked up well with Iliass Bel Hassani to pull one back for Heracles only two minutes later, but it was never going to be enough for the hosts to escape a ninth defeat from 10 games this campaign. body check tags ::