Heracles have suffered a sixth consecutive defeat in the Eredivisie with a 4-1 loss at home to FC Twente.
The strugglers took the lead on 16 minutes through Wout Weghorst, but Twente got themselves level eight minutes later as Luc Castaignos arrived in the box to poke the ball home.
Castaignos found the net again with a header on 42 minutes which put the visitors in front, and they made it 3-1 just 60 seconds later thanks to Hakim Ziyech's composed finish.
Twente then secured the points 15 minutes from time when Youness Mokhtar curled the ball in from the edge of the penalty area following a quick break.