Eden Hazard will captain Lille on his final appearance for the club as they take on Nancy at the Stade Lille-Metropole.
Joe Cole also starts for Rudi Garcia's men, with Benoit Pedretti and Antonio Mavuba starting from the bench.
Djamel Bakar must also settle for a place on Nancy's bench as they start with Benjamin Moukandjo, Lossemy Karaboue and Bakaye Traore upfront.
Lille: Landreau, Digne, Beria, Bonnart, Basa, Balmont, Gueye, Payet, Hazard, Cole, De Melo
Nancy: Ndy Assembe, Loties, Bayal, Lemaitre, Sane, Puygrenier, Mangani, Mollo, Moukandjo, Traore, Karaboue