SM
| Venue: OPEL Arena |
Mainz 05 | ||
| G | 22 | Florian Müller |
| CD | 42 | Alexander Hack |
| CD-L | 19 | Moussa Niakhate |
| CD-R | 16 | Stefan Bell |
| CM-L | 14 | Pierre Kunde S  |
| CM-R | 35 | Leandro Barreiro S |
| AM | 5 | Jean-Paul Boëtius S |
| LM | 3 | Aarón Martín S |
| RM | 18 | Daniel Brosinski |
| CF-L | 7 | Robin Quaison |
| CF-R | 9 | Jean-Philippe Mateta |
| Sub | 25 | Jean-Philippe Gbamin |
| Sub | 38 | Gerrit Holtmann |
| Sub | 21 | Karim Onisiwo |
| Sub | 20 | Anthony Ujah |
| Sub | 10 | Alexandru Maxim |
| Sub | 8 | Levin Öztunali |
| Sub | 27 | Robin Zentner |
Bayer Leverkusen | ||
| G | 1 | Lukas Hradecky |
| CD-L | 5 | Sven Bender |
| CD-R | 4 | Jonathan Tah |
| LB | 18 | Wendell S |
| RB | 23 | Mitchell Weiser |
| CM | 20 | Charles Aránguiz |
| LM | 10 | Julian Brandt S |
| RM | 29 | Kai Havertz S |
| F | 31 | Kevin Volland |
| LF | 9 | Leon Bailey |
| RF | 38 | Karim Bellarabi |
| Sub | 16 | Tin Jedvaj |
| Sub | 13 | Lucas Alario |
| Sub | 15 | Julian Baumgartlinger |
| Sub | 28 | Ramazan Özcan |
| Sub | 6 | Aleksandar Dragovic |
| Sub | 21 | Dominik Kohr |
| Sub | 7 | Paulinho |
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