Fernandinho claims Manchester City's poor record at Anfield will count for nothing this weekend.
The Premier League champions travel to current leaders Liverpool for an eagerly-awaited clash on Sunday.
Despite City's recent domestic dominance, they have been unable to break a long-running Merseyside hoodoo.
City have won just once at Anfield since 1981 – and that was 16 years ago.
Not even the arrival of Pep Guardiola as manager has brought a change of luck, with the Spaniard's four trips to the ground including the chastening 3-0 Champions League quarter-final loss in 2018.
There is plenty riding on the latest meeting, with City looking to cut into the Reds' six-point lead at the summit.
Fernandinho, who has been forced to reinvent himself as a defender this season due to injuries, said: "There's always a first time in the life, no? We are searching for this first time to win at Anfield.
"We go there and try to win the game. The mentality is always try to win the game. I am confident we can go there and try to win."
"We had to defend a little bit more than usual but Sunday we go there to try to win the game from the first minute."
City are still waiting on updates on Ederson, who suffered a thigh injury in the first half.
Along with playmaker David Silva, who missed the trip to Italy with a muscular problem, the Brazilian is doubtful for the weekend.
