The Egypt international was an unused substitute for Sunday's goalless Merseyside derby draw having missed the team's warm-up game the previous week.
Left-back Andy Robertson is also set to return having missed the game at Goodison Park, which is timely as stand-in James Milner has been ruled out with a hamstring injury, while defender Joel Matip is sidelined with a toe problem.
Schlupp, who has not played since December, suffered an injury when training resumed while Tomkins has not recovered from a previous problem and Kelly has a calf knock.
Eagles boss Roy Hodgson has reported no other selection worries.
Liverpool provisional squad: Alisson, Alexander-Arnold, Van Dijk, Gomez, Robertson, Fabinho, Henderson, Wijnaldum, Salah, Firmino, Mane, Adrian, Lovren, Williams, Lallana, Keita, Oxlade-Chamberlain, Minamino, Origi, Elliott, Jones.
Crystal Palace provisional squad: Guaita, Ward, Dann, Cahill, Van Aanholt, Kouyate, McArthur, McCarthy, Ayew, Zaha, Benteke, Hennessey, Sakho, Riedewald, Milivojevic, Meyer, Townsend, Tosun.