Lorient manager Christian Gourcuff has made two changes to the side that were thumped 4-0 at Paris Saint-Germain last weekend.
Fabien Audard and Jeremie Aliadiere drop out of the squad, with Florent Chaigneau and Alain Traore coming into the starting lineup.
Meanwhile, Hubert Fournier has opted against making any alterations to his Reims team following their 4-2 win at Bastia last time out.
Nicolas De Preville and Odair Fortes retain their places in attack.
Lorient: Chaigneau, Baca, Ecuele Manga, Guerreiro, Kone, Lautoa, Barthelme, Jouffre, Traore, Aboubakar, Monnet-Paquet
Reims: Agassa, Mandi, Signorino, Tacalfred, Weber, Devaux, Krychowiak, Oniangue, Ayite, De Preville, Fortes