Boss Pep Guardiola called on Manchester City to remain mentally strong after their collapse at Wolves dealt a hammer blow to their fading Premier League title hopes.
The defending champions lost a 2-0 lead to slump to a 3-2 defeat on Friday after playing almost 80 minutes with 10 men following Ederson's red card.
Matt Doherty's 89th-minute strike capped Wolves' comeback after Adama Traore and Raul Jimenez had hauled the hosts level.
Manager Nuno Espirito Santo said: "We performed very well, it was an incredible night. The reality of the game changes when Manchester City have one man less.
"We played well, we tried. We conceded a mistake in the second half for the goal but we didn't change our way and kept looking for solutions.
"We keep on going and keep believing, the second goal was a mistake and we shouldn't do it.
"I would not have been disappointed even if we did not win because we played well."