Tottenham Hotspur face Manchester United at Old Trafford on Monday evening, aiming to make it three wins from three to kick off the campaign.
The Lilywhites have a terrible past record at the Theatre of Dreams, though, losing on 21 of their previous 26 visits during the Premier League era.
After shuffling his pack slightly for the 3-1 win over Fulham last weekend, Mauricio Pochettino has some tough selection calls to make for the concluding fixture of matchday three.
With that in mind, Sports Mole predicts how Spurs will set up for their showdown against United.
Out: Cameron Carter-Vickers, Juan Foyth, Vincent Janssen, Son Heung-min
Doubtful: Josh Onomah, Victor Wanyama, Hugo Lloris
Pochettino will be pleased that his returning World Cup stars have hit the ground running over the past fortnight, leaving him with plenty of options across the field, despite the club's failure to bring in a single new face during the summer.
The biggest headache for the former Southampton boss is skipper Lloris's arrest for an alleged drink-driving offence on Friday, which may force a change in goal - Michel Vorm being the obvious replacement between the sticks if that is the case.
Tottenham's back three came good in the end against Fulham last time out, with Kieran Trippier and Ben Davies being given licence to push forward, while at the same time shoehorning Toby Alderweireld, Jan Vertonghen and Davinson Sanchez into the side.
Son is the only big-name absentee for this weekend's clash due to his Asian Games commitments, but Lucas Moura has taken his impressive pre-season form into the campaign proper, and centre-forward Harry Kane finally got off the mark with his first August goal at the 15th attempt last week.
