A renewal of hostilities with major implications in the Premier League title and top-four races occurs at Anfield on Sunday lunchtime as Liverpool prepare for battle against Manchester United.
Erik ten Hag's men find themselves three places and 10 points better off than their Merseyside counterparts, who fell to a 2-1 defeat to the Red Devils at Old Trafford back in August.
However, not since January 2016 have Liverpool lost a Premier League home game against Man United, who have felt the full force of Mohamed Salah's powers over the past couple of years.
Here, Sports Mole takes a closer look at Salah's record against the 20-time English champions ahead of Sunday's mouthwatering contest.
Despite getting off to a slow start against Man United - failing to score or assist in each of his first four meetings with them - the Red Devils are now one of three of Salah's favourite opponents, having quickly surged into double figures in the goals column.
Indeed, the Egyptian wing king has struck 10 goals and set up two more in his 11 clashes with Man United - only against Tottenham Hotspur and Manchester City has he also scored in the double figures, but he has faced the Lilywhites 17 times and the champions 18 times during his prolific career.
It may come as a surprise to learn that Salah's first goal against Man United did not arrive until January 2020 - netting an injury-time second for his side in a late 2-0 win, being assisted by a long pass from goalkeeper Alisson Becker.
Salah briefly returned to his ineffective ways against Man United in a goalless stalemate 12 months later, but a brace in a 3-2 FA Cup defeat to the Red Devils at Old Trafford one week later sparked a goal rush that is yet to cease.
The former Chelsea man has found the back of the net in each of his last four Premier League appearances against the Red Devils, starting with another late counter-attacking goal in a 4-2 Old Trafford win in May 2021.
A sensational 2021-22 campaign for Liverpool against Man United saw the Reds win both games by an aggregate scoreline of 9-0, during which Salah directly contributed to seven of those goals - scoring five himself and setting up two more.
After becoming the first-ever player to score a Premier League hat-trick against Man United at Old Trafford in an enthralling 5-0 win, Salah struck another brace in a 4-0 Anfield success in April 2022, while also chalking up one assist in both games.
Liverpool's consolation goal in August's Old Trafford defeat would come from the head of the 30-year-old, who is unsurprisingly Liverpool's highest all-time goalscorer against Man United - Steven Gerrard is only one behind with nine.
While his goalscoring feats this season may have been outshone by a certain Erling Braut Haaland, 20 strikes in all tournaments is hardly an abysmal record for Salah, who can be expected to subject Luke Shaw to a torrid afternoon in search of a goal against Man United for a sixth successive game.
