Leicester vs. Chelsea (Saturday, 12.30pm)
Leicester City play host to Chelsea in the Premier League on Saturday afternoon looking to bounce back from the disappointment of missing out on a place in the EFL Cup final.
Having failed to win their last two top-flight fixtures, the Blues make the trip to the King Power Stadium looking to close the gap on the third-placed Foxes to five points.
We say: Leicester City 3-1 Chelsea
While Chelsea have had a longer break than their hosts, we cannot help but feel that Leicester's exit from the EFL Cup will only act as extra motivation in this game. Despite Chelsea possessing a strong away record, we are backing the Foxes to run out comfortable victors.
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> How Chelsea could line up against Leicester
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Bournemouth vs. Aston Villa (Saturday, 3pm)
Bournemouth and Aston Villa square off in the Premier League on Saturday afternoon with just two points separating the clubs in the standings.
Villa sit in 16th position after picking up four points from their last two outings, while Bournemouth remain in the relegation zone despite their recent victory over Brighton & Hove Albion.
We say: Bournemouth 1-2 Aston Villa
Despite possessing home advantage and having recently got the better of Brighton, we feel that Bournemouth are up against it in this match. Both clubs would probably accept a share of the spoils, but we are backing Villa to score late on to move clear of the drop zone.
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Crystal Palace vs. Sheffield United (Saturday, 3pm)
Sheffield United make the trip to Selhurst Park to face Crystal Palace sitting in eighth position in the Premier League standings.
However, just three points separate the Blades and the Eagles, who have won just one of their last 10 matches in all competitions.
We say: Crystal Palace 1-2 Sheffield United
United have been excellent on their travels this season and we feel that they will strengthen their away record on Saturday. While the fresh faces at Palace may give them a lift, they may struggle to break down a strong Blades backline.
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Liverpool vs. Southampton (Saturday, 3pm)
Liverpool's final match before the midseason break sees them welcome an in-form Southampton side to Anfield on Saturday.
Jurgen Klopp's champions-elect continued their procession towards the title with a 2-0 win over West Ham United in their game in hand on Wednesday night, but they face a Southampton side flying up the Premier League table.
We say: Liverpool 2-0 Southampton
Southampton were a whisker away from taking points off Liverpool in August - something only one team has managed to do since March - but a trip to Anfield is a different proposition entirely. Liverpool seem simply unstoppable at the moment, particularly at home, and it is impossible to back against anything other than another win for the runaway league leaders.
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> How Liverpool could line up against Southampton
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Newcastle vs. Norwich (Saturday, 3pm)
Newcastle United welcome Norwich City to St James' Park on Saturday, with the home side looking to avoid being sucked back into the relegation battle.
Norwich are currently bottom of the Premier League, 13 points adrift of Steve Bruce's side in 14th, but the Canaries did beat Newcastle handily in the reverse fixture last August.
We say: Newcastle United 1-1 Norwich City
This will be a match of two clashing styles at St James' Park, with Newcastle likely to offer a physical examination of Norwich's young team. However, the away side do possess quality in the attacking areas and could manage to come away with a point.
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Watford vs. Everton (Saturday, 3pm)
Watford face Everton at Vicarage Road on Saturday in the Premier League, with the home side looking to continue their resurgence under new manager Nigel Pearson.
Everton have also seen an improvement since the arrival of Carlo Ancelotti, but both sides are still well below their expectations at the start of the season.
We say: Watford 1-0 Everton
Watford are unbeaten at home since Pearson's arrival and should be able to continue that run on Saturday. Everton are better under Ancelotti but remain a work in progress and go into this match as second favourite.
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West Ham vs. Brighton (Saturday, 3pm)
West Ham United play host to Brighton & Hove Albion on Saturday, with both sides looking to rediscover some form and start moving away from the relegation places.
West Ham and Brighton have each taken one point from their last three Premier League matches and either side could find themselves in the dropzone if they lose on Saturday and results elsewhere go against them.
We say: West Ham United 1-2 Brighton & Hove Albion
In a battle between one of the worst home sides in the Premier League and one of the worst away sides, a draw seems inevitable. However, Brighton have looked the better team this season and if they play their best, they can earn a valuable win on Saturday.
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Man Utd vs. Wolves (Saturday, 5.30pm)
Manchester United will be looking to return to winning ways in the Premier League when they welcome Wolverhampton Wanderers to Old Trafford in Saturday's late kickoff.
Both United and Wolves have collected 34 points from their 24 league matches this season, but the Red Devils are fifth in the table on goal difference while Wolves are behind Tottenham Hotspur in seventh.
We say: Manchester United 2-1 Wolverhampton Wanderers
This is a very, very difficult match to predict for obvious reasons. Both managers will feel that they can pick up a positive result, but the arrival of Fernandes is huge for the 20-time English champions. We expect the Red Devils to record a narrow win at the conclusion of a very tight Premier League match.
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Burnley vs. Arsenal (Sunday, 2pm)
Burnley and Arsenal meet at Turf Moor on Sunday afternoon with the two teams locked on the same points in the Premier League standings.
However, as a result of Burnley's inferior goal difference, as many as three places separate the clubs, with Arsenal sitting in 10th spot and the Clarets down in 13th position.
We say: Burnley 1-2 Arsenal
While Burnley have gotten back on track in recent matches, we are predicting that Arsenal will continue to show a different side to their game at Turf Moor, grinding out a much-needed three points to get them back in the hunt for the top six.
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> How Arsenal could line up against Burnley
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Tottenham vs. Man City (Sunday, 4.30pm)
Arguably the pick of this weekend's Premier League action will take place in the English capital on Sunday as Tottenham Hotspur prepare to welcome Manchester City.
Spurs are currently sixth in the Premier League table, six points off fourth-placed Chelsea, while reigning champions City occupy second, some 19 points behind runaway leaders Liverpool.
We say: Tottenham Hotspur 1-2 Manchester City
City are not the same team that they were last season, and there is no question that Mourinho is capable of setting a side up to frustrate and ultimately overcome the champions. City's recent record in London is excellent, though, and we just fancy the visitors to pick up a narrow win on Sunday afternoon.
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> How Tottenham could line up against Man City
> How Man City could line up against Tottenham
> Click here for Tottenham's latest injury and suspension news ahead of this match
> Click here for Man City's latest injury and suspension news ahead of this match