The champions face the leaders in the headline fixture of gameweek 23 as a faltering Liverpool welcome in-form Manchester City to Anfield on Sunday.
Fellow high-flyers Manchester United and Leicester City will be looking to capitalise on any dropped points in that game when they face Everton and Wolverhampton Wanderers respectively.
Click play below to watch or listen to Sports Mole Editor Barney Corkhill and Football Editor Matt Law discuss their predictions for all 10 Premier League fixtures in gameweek 23.
Watch the full discussion here:
Or you can listen to the full podcast here:
SATURDAY
12.30pm - Aston Villa vs. Arsenal (0:11)
3pm - Burnley vs. Brighton & Hove Albion (5:02)
3pm - Newcastle United vs. Southampton (9:40)
5.30pm - Fulham vs. West Ham United (15:33)
8pm - Manchester United vs. Everton (20:26)
SUNDAY
12pm - Tottenham Hotspur vs. West Bromwich Albion (26:47)
2pm - Wolverhampton Wanderers vs. Leicester City (32:42)
4.30pm - Liverpool vs. Man City (36:33)
7.15pm - Sheffield United vs. Chelsea (43:47)
MONDAY
8pm - Leeds United vs. Crystal Palace (49:45)
