The North London derby headlines gameweek 28 of the Premier League season as Arsenal and top-four hopefuls Tottenham Hotspur go head to head at the Emirates Stadium.
That is by no means the only important game of the weekend, though, with Manchester United hosting West Ham United in a battle between two other teams in that Champions League race, and a South Coast derby between Southampton and Brighton & Hove Albion.
Click play below to watch or listen to Sports Mole Editor Barney Corkhill and Football Editor Matt Law discuss their predictions for all 10 matches this weekend.
Watch the full discussion here:
Or you can listen to the full podcast here:
FRIDAY
8pm - Newcastle United vs. Aston Villa (0:18)
SATURDAY
12.30pm - Leeds United vs. Chelsea (5:04)
3pm - Crystal Palace vs. West Bromwich Albion (11:22)
5.30pm - Everton vs. Burnley (15:12)
8pm - Fulham vs. Manchester City (19:48)
SUNDAY
12pm - Southampton vs. Brighton & Hove Albion (26:00)
2pm - Leicester City vs. Sheffield United (31:58)
4.30pm - Arsenal vs. Tottenham Hotspur (37:53)
7.15pm - Manchester United vs. West Ham United (43:46)
MONDAY
8pm - Wolverhampton Wanderers vs. Liverpool (51:08) body check tags ::