Manchester United have been dealt another injury blow with news that Robin van Persie was substituted at half-time during the Netherlands' 4-1 win over Hungary.

Japanese international Shinji Kagawa has also suffered an injury while playing for his country during this international break.

Van Persie has injured his thigh, although Dutch coach Louis van Gaal has said that it does not look serious.

"We took off Van Persie for precautionary measures," said Van Gaal. "It doesn't seem to be too serious. We didn't want to take any risks."

Van Persie has scored four goals for the Red Devils since his move from Arsenal.