Brighton vs. Brentford (Wednesday, 7.30pm)
While Roberto De Zerbi's side are looking to extend their unbeaten home run to six matches, Thomas Frank's men will endeavour to stretch their undefeated streak over the Seagulls to three games.
We say: Brighton & Hove Albion 2-2 Brentford
Although both Brighton and Brentford are having to cope without a number of first-team regulars, the two teams will be confident in their own abilities to navigate their way towards maximum points on Wednesday.
The Seagulls will be regarded as slight favourites, but there is little to separate these two sides and we believe they will ultimately cancel each other out in an entertaining score draw.
Fulham vs. Nott'm Forest (Wednesday, 7.30pm)
We say: Fulham 2-1 Nottingham Forest
In a game rife with spectacular strikes, Fulham could feel hard done by not to come away from Anfield with at least a share of the spoils, and Forest's attackers have a tough act to follow to replicate Liverpool's sensational efforts on Merseyside.
Cooper's men often struggle to breach opposing backlines on the road, though, and while the more superstitious Fulham fans may possess a sense of trepidation given their sequence of home results, Silva's fired-up side should have enough to return to winning ways here.
Sheff Utd vs. Liverpool (Wednesday, 7.30pm)
Amid talk of Paul Heckingbottom facing the sack, Sheffield United return to face the disgruntled Bramall Lane faithful when they host Liverpool in Wednesday's Premier League clash.
We say: Sheffield United 1-4 Liverpool
Liverpool's efforts to keep the opposition at bay on the road have been futile so far this season, and the Reds were punished for a few sequences of sloppy play against Fulham, where Alisson Becker was not available to come up with his customary match-saving moments.
An anticipated change of management could breathe new life into a depleted Blades XI, but their defensive issues will not be solved overnight, and another chastening afternoon awaits the hosts against Liverpool's rampant attacking contingent.
Crystal Palace vs. Bournemouth (Wednesday, 7.30pm)
While the Eagles currently sit 12th in the top-flight standings with 16 points from 14 matches, the Cherries are three points and four places further back in 16th spot.
We say: Crystal Palace 1-1 Bournemouth
Both Crystal Palace and Bournemouth will view Wednesday's clash as a winnable game and know that three points secured an Selhurst Park would provide them with a much-needed confidence boost ahead of next weekend's challenging matches against Liverpool and Man United respectively.
Although the Eagles have fared better in this fixture in recent seasons, their dip in form has coincided with improvements made at Bournemouth, so a closely-fought score draw could be on the cards this time around.
Aston Villa vs. Man City (Wednesday, 8.15pm)
Seeking to avoid a fourth successive game without a win in the Premier League, reigning champions Manchester City travel to Villa Park to test their mettle against a high-flying Aston Villa outfit on Wednesday night.
Only one point separates these two teams in the top-flight table, with the Citizens in third place sitting just ahead of the Lions in fourth spot after 14 matches.
We say: Aston Villa 1-2 Manchester City
No Premier League teams have scored more goals this season than Man City (36) and Aston Villa (33), who are both set to view Wednesday's intriguing contest as a challenging one in their quest to return to winning ways.
Villa have every right to feel optimistic of success considering their outstanding home form, but if any team are to burst their bubble it could well be Man City, who boast a strong head-to-head record in this fixture and will be fired up to make amends following their recent dip in form.
Man Utd vs. Chelsea (Wednesday, 8.15pm)
We say: Manchester United 1-1 Chelsea
For all of Man United's perpetual struggles in the attacking third, Ten Hag's side are seldom torn to shreds at the back, and one never truly knows what to expect from Pochettino's Chelsea charges.
Goals are virtually a guarantee at both ends when the Blues step out onto the field, and such a theme should continue at Old Trafford, but we simply cannot pick a clear winner and expect a return to drawing ways for the two clubs this week.
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