With just one victory from five, Ronald Koeman's men will be keen to register a morale-boosting win and set off on the road to prove that they are not a one-season wonder.
We say: Southampton 1-2 Manchester United
As inconsistent as Southampton have been early doors, the visit of United might be just what the doctor ordered as they bid to kick-start their stuttering season. That being said, the Red Devils will be on a high after beating Liverpool, despite their midweek setback, and we reckon that Van Gaal will one-up Koeman with a narrow win.
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