Montpellier HSC have moved further away from the Ligue 1 relegation zone after they came from behind to beat Reims.
The visitors were ahead inside 12 minutes at the Stade de la Mosson when Diego's set piece was coolly headed home by Anthony Weber.
However, La Paillade hit back at the midway point in the first half as Bryan Dabo's pinpoint corner was nodded into the net from close range by Mustapha Yatabare.
Montpellier then took the lead on 69 minutes when Souleymane Camara rifled the ball into the back of the net, leaving Reims keeper Kossi Agassa with no chance.
Stade thought they had equalised after Diego's shot from distance left Laurent Pionnier beaten, but it came back off the bar.
Instead, it was the hosts who sealed victory in the dying moments when ex-Blackburn Rovers player Dabo headed Ryad Boudebouz's cross beyond the reach of Agassa.