Despite playing for over an hour with just 10 men, the Netherlands have held Colombia to a goalless draw in Amsterdam to extend their unbeaten run to 17 games.
Jeremain Lens was shown a straight red card during a heated first half following an aggressive push on Pablo Armero, who escaped unpunished after aiming an off-the-ball kick at the Dynamo Kyiv forward.
Rafael van der Vaart then limped off the field and had to be substituted after being injured by a dangerous tackle from Abel Aguilar, who received a yellow card.
Siem de Jong also left the field prematurely, having picked up a knock during an innocuous looking challenge.
Columbia did not register a single shot in the first half as, prior to Lens's dismissal, Louis van Gaal's men dominated possession.
The hosts went close breaking the deadlock on seven minutes when Van der Vaart struck the crossbar from long range.
Visitors Colombia grew in confidence after the break and Radamel Falcao came close to winning it for the South Americans, but his firm header was saved by Jasper Cillessen.
Chelsea left-back Patrick van Aanholt made his senior international debut, coming on as a substitute in second-half stoppage time.