First up for Newcastle is an away game against West Ham United on the opening Saturday of the new season, and they welcome Brighton & Hove Albion to St James' Park in their first home outing.
The turn of the year looks particularly difficult for the Magpies, with back-to-back games against Manchester City and Liverpool bringing an end to 2020 before starting the New Year against Leicester City, Sheffield United and Arsenal.
Newcastle then face those five teams in succession again towards the end of the campaign before finishing at home to newly-promoted Fulham.
SEPTEMBER
12: West Ham (a)
19: Brighton (h)
26: Tottenham (a)
OCTOBER
3: Burnley (h)
17: Man Utd (h)
24: Wolves (a)
31: Everton (h)
NOVEMBER
7: Southampton (a)
21: Chelsea (h)
28: Crystal Palace (a)
DECEMBER
5: Aston Villa (a)
12: West Brom (h)
15: Leeds (a)
19: Fulham (h)
26: Man City (a)
28: Liverpool (h)
JANUARY
2: Leicester (h)
12: Sheff Utd (a)
16: Arsenal (a)
27: Leeds (h)
30: Everton (a)
FEBRUARY
3: Crystal Palace (h)
6: Southampton (h)
13: Chelsea (a)
20: Man Utd (a)
27: Wolves (h)
MARCH
6: West Brom (a)
13: Aston Villa (h)
20: Brighton (a)
APRIL
3: Tottenham (h)
10: Burnley (a)
17: West Ham (h)
24: Liverpool (a)
MAY
1: Arsenal (h)
8: Leicester (a)
12: Man City (h)
15: Sheff Utd (h)
23: Fulham (a)