Paraguay are expected to deploy Angel Romero in attack for Tuesday's Copa America clash with Bolivia, with the forward having netted six goals in 24 appearances for his nation.
He will be complemented by Paraguay's key man Miguel Almiron as part of a front two, built on solid foundations at the back.
Almiron has made himself a crucial cog for Newcastle United with consistent performances behind the front line, hugely boosting their attack with impressive build-up play.
At the other end of the pitch, West Ham United centre-back Fabian Balbuena should come into the side at the heart of the defence, despite featuring sporadically for the Hammers in the Premier League this season.
He should line up alongside Junior Alonso and captain Gustavo Gomez in the middle of a sturdy back five.
They will shield experienced goalkeeper Antony Silva, who plies his trade in Mexico for Puebla.
In front of the defence, manager Eduardo Berizzo should deeply the established midfield unit of Mathias Villasanti, Gaston Gimenez and Angel Cardozo Lucena.
Paraguay possible starting lineup: Silva; Rojas, Gomez, Balbuena, Alonso, Arzamendia; Villasanti, Gimenez, Cardozo Lucena; Romero, Almiron
> Click here to see how Bolivia could line up for this clash
