Real Madrid will reportedly be without the services of Isco for next week's Champions League semi-final second leg with Bayern Munich at the Bernabeu.
According to Marca, the Spain international picked up a shoulder injury in Madrid's 2-1 win over Bayern at the Allianz Arena on Wednesday night.
The report claims that tests have not yet determined the extent of the problem, but Isco is seen as a major doubt for the second leg against the German champions, with the injury expected to rule him out of action for one week.
Los Blancos are also facing the possibility of being without key defender Dani Carvajal, who picked up a thigh problem during the same match.
Marcelo and Marco Asensio were on the scoresheet for Madrid in Munich as the reigning European champions moved a step closer to yet another Champions League final.