Real Madrid attacker Isco has withdrawn from the Spain squad after picking up a muscular injury during a training session.

The 23-year-old, who has 11 international caps to his name, was included in the La Roja squad for their upcoming friendlies against England and Belgium.

However, after feeling "discomfort" during a training session on Wednesday, the midfielder has been forced to declare himself unavailable.

"[Isco] carried out an individual training session, separate from the team, due to the discomfort felt upon arriving to the practice," read a statement from the Spanish Football Federation.

"After undergoing several medical tests and after analysing the results, and sharing them with his club, Isco has left the national team meet-up."

Isco is the latest of a number of Real Madrid players to suffer injury this season.