Villarreal vs. Valladolid (Saturday, 1.00pm)
Fresh from their impressive triumph at the Santiago Bernabeu, in-form Villarreal welcome Real Valladolid to the Estadio de la Ceramica in La Liga on Saturday.
While the hosts have put together a three-game unbeaten run on home soil, the visitors are seeking to avoid a fifth successive away match without a win.
We say: Villarreal 2-0 Real Valladolid
Valladolid can ill-afford to drop more points if they wish to avoid being dragged into the relegation zone, but considering the strong run of form Villarreal possess, we expect the hosts to secure a routine victory on Saturday to boost their top-four hopes.
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Athletic Bilbao vs. Real Sociedad (Saturday, 3.15pm)
The latest instalment of the Basque derby takes place at the San Mames Barria as Athletic Bilbao play host to Real Sociedad in La Liga on Saturday.
While the hosts are battling to secure a top-six finish this term, the visitors are seeking to consolidate their place in the top four and qualify for next season's Champions League.
We say: Athletic Bilbao 2-2 Real Sociedad
An entertaining contest could be on the cards this weekend between two teams seeking to boost their European hopes by claiming maximum points against their closest rivals.
Real Sociedad came out on top in the reverse fixture earlier this year, but we believe that Athletic Bilbao will come away with at least a point in front of their own fans this time around.
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Betis vs. Espanyol (Saturday, 5.30pm)
Real Betis welcome Espanyol to the Estadio Benito Villamarin for a crucial La Liga encounter at both ends of the table on Saturday.
Both clubs have slipped down the standings recently following poor runs of form.
We say: Real Betis 2-1 Espanyol
Having Canales available could be crucial for Betis with any hopes of Champions League football potentially hinging on this result.
Espanyol are often a threat in attack but just cannot get over the line with a victory at the moment.
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Cadiz vs. Real Madrid (Saturday, 8.00pm)
Real Madrid will be aiming to return to winning ways in Spain's top flight when they resume their domestic campaign away to Cadiz on Saturday night.
Los Blancos suffered a 3-2 loss to Villarreal in La Liga last weekend and have now dropped 13 points behind division leaders Barcelona in the table with 10 games left, while Cadiz occupy 14th, four points clear of the relegation zone.
We say: Cadiz 1-2 Real Madrid
Cadiz will certainly be the fresher of the two sides, while Real Madrid are expected to rest a number of important players, but we still believe that the reigning champions will be able to navigate their way to all three points in Saturday's contest.
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> How Real Madrid could line up against Cadiz
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