Athletic Bilbao vs. Eibar (Saturday, 1.00pm)
Saturday's La Liga action kicks off with a Basque derby between relegation-threatened Eibar and regional heavyweights Athletic Bilbao at the San Mames.
Eibar could find themselves at the bottom of the table if they lose on Saturday and other results go against them, while Athletic could finish the weekend in eighth place, in hot pursuit of the division's highly coveted European spots.
We say: Athletic Bilbao 2-0 Eibar
It is difficult to see Eibar coming away with anything from this encounter, with Athletic looking the much more convincing outfit. We are going with a home win and goals from Inaki Williams and Iker Muniain.
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Celta Vigo vs. Real Madrid (Saturday, 3.15pm)
Real Madrid will be looking to make it three victories in a row in all competitions when they continue their La Liga campaign away to Celta Vigo on Saturday afternoon.
Los Blancos are currently third in the table, six points behind leaders Atletico Madrid, while Celta occupy 10th position, having picked up 34 points from their 27 league games this term.
We say: Celta Vigo 1-2 Real Madrid
Celta are more than capable of beating Madrid, and Zidane will be wary of suffering a Champions League hangover on Saturday afternoon. As a result, the Frenchman is expected to resist the temptation to make wholesale changes, and the champions should have enough to pick up all three points in Vigo.
> Click here to read our full preview for this match
> How Celta Vigo could line up against Real Madrid
> How Real Madrid could line up against Celta Vigo
> Real Madrid injury, suspension list vs. Celta Vigo
Huesca vs. Osasuna (Saturday, 5.30pm)
Bottom-of-the-league Huesca will entertain Osasuna at El Alcoraz on Saturday afternoon in a clash that could have big implications on this season's relegation battle.
A win for the hosts could see the La Liga minnows leapfrog Eibar and Alaves into 18th place, while three points for Osasuna could propel Jagoba Arrasate's men into the upper reaches of the league.
We say: Huesca 3-2 Osasuna
Games involving Huesca are always difficult to call because Pacheta's men play with such an unpredictable, chaotic intensity, and it is precisely because of that consideration that we think Huesca are going to come away from this five-goal thriller with all three points.
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Real Valladolid vs. Sevilla (Saturday, 8.00pm)
Julen Lopetegui's high-flying Sevilla side will look to keep pace with La Liga's heavyweights when they take on Real Valladolid at the Estadio Nuevo Jose Zorilla on Saturday.
Valladolid, who have not beaten Sevilla in La Liga since 2012, could go a long way in securing their top-flight credentials with three points against the Andalusian outfit.
We say: Real Valladolid 0-2 Sevilla
Valladolid have done enormously well to climb out of La Liga's drop zone, but taking points off Sevilla may be a step too far for Sergio's men. We are going with a 2-0 for Sevilla, with En-Nesyri no doubt netting another for the club.