Granada vs. Villarreal (Saturday, 1.00pm)
Granada will welcome Villarreal to the Nuevo Estadio de Los Carmenes on Saturday for a meeting with significant importance at both ends of the La Liga table.
The visitors find themselves battling for a spot in the top six, while their hosts sit just one place and four points above the relegation zone after four straight league defeats.
We say: Granada 0-2 Villarreal
Given the contrasting form of the two sides, we see Villarreal returning home with all three points on Saturday.
The Yellow Submarine have seemingly found their feet recently, built on their solid defensive foundations, and they are expected to get past a Granada side lacking any confidence or momentum.
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Osasuna vs. Atletico (Saturday, 3.15pm)
Atletico Madrid travel to Osasuna on Saturday, as the defending champions aim to strengthen their claim for a top-four finish in the La Liga table this season.
Diego Simeone's side suffered another setback last time out, losing to strugglers Levante to remain fifth in the Spanish top flight, while their hosts sit ninth after a 3-0 win last weekend.
We say: Osasuna 1-1 Atletico Madrid
Atletico Madrid have been far from convincing so far this season, and, with plenty of momentum and home advantage, we back Los Rojillos to earn a valuable result.
While Simeone's men will be keen to bounce back from a disappointing defeat, their attention may be divided with a key Champions League clash looming, and Saturday will certainly not be a straightforward affair for the faltering champions.
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Cadiz vs. Getafe (Saturday, 5.30pm)
Two sides separated by six points at the bottom end of the La Liga table will do battle on Saturday, as Cadiz play host to Getafe.
The home side currently find themselves in 19th spot, five points adrift of safety, while their visitors have a five-point gap between themselves and the drop zone after their recent climb.
We say: Cadiz 0-1 Getafe
Getafe came out as 4-0 winners in the reverse future in November, and, while we do not see this affair being that much of a landslide, we do back the Azulones to pick up another victory.
Although Cadiz may be showing gradual improvement of their own, Flores's men have looked a completely new side in recent months, and we see them leaving with a seventh league win of the campaign.
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Real Madrid vs. Alaves (Saturday, 8.00pm)
Real Madrid will be bidding to return to winning ways on Saturday evening when they continue their La liga campaign at home to relegation-threatened Alaves.
Los Blancos are currently top of the table, four points clear of second-placed Sevilla, while Alaves occupy 18th position, four points from the safety of 17th position heading into the next set of fixtures.
We say: Real Madrid 2-0 Alaves
Real Madrid are in a need of a confidence-boosting win amid a difficult run of form, and we are fully expecting the home side to triumph this weekend. Alaves impressed against Valencia last time out and won at Bernabeu last term, but Ancelotti's side should have enough to collect all three points here.
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> How Real Madrid could line up against Alaves
> Real Madrid injury, suspension list vs. Alaves body check tags ::
