Isco is reportedly 'a ticking time bomb' at Real Madrid, and the European champions could be forced to sell the Spain international either in January or at the end of the season.
Isco has struggled for regular action since Santiago Solari replaced Julen Lopetegui as head coach earlier this season, leading to suggestions that the 26-year-old could leave the Bernabeu.
The midfielder currently has a difficult relationship with Los Blancos' supporters, meanwhile, and that has been made worse after it emerged that he refused to accept the captain's armband during the Champions League clash with CSKA Moscow on Wednesday night.
According to Goal.com, Isco is 'frustrated' at the Bernabeu, while club president Florentino Perez 'is growing disenchanted' with current events, which could force the Spanish giants into a sale.
Isco, who has been linked with a number of Premier League clubs as well as Juventus, has a £630m release clause inserted into his current contract, which runs until the end of the 2021-22 campaign.
