Spain manager Luis Enrique is working without some high-profile names for Saturday's UEFA Nations League clash with Switzerland in League A Group 2.
La Roja are coping with the absences of Mikel Oyarzabal and Aymeric Laporte due to injury, while Thiago Alcantara, Ansu Fati, Sergio Ramos and David de Gea have all been left at home.
There is room for two uncapped strikers in the form of Nico Williams and Borja Iglesias, as Enrique seeks to take some of the pressure off of Alvaro Morata's shoulders.
Morata can still expect to feature from the off on Saturday, with Ferran Torres and Pablo Sarabia - who scored the winner against Switzerland in June - providing support from the flanks.
Enrique has the opportunity to field a full Barcelona midfield of Gavi, Pedri and Sergio Busquets, but the Roja boss may prefer the experienced Koke over Pedri given his constant fitness struggles during his fledgling career.
The absence of Laporte should see Eric Garcia and Pau Torres pair up in the heart of defence, as Unai Simon fends off competition from David Raya and Robert Sanchez to start in goal.
Despite losing his place in the Barcelona XI to Alejandro Balde, Jordi Alba is set to start at left-back for Spain as Dani Carvajal earns just his 30th cap for the national team on the opposite side.
Spain possible starting lineup: Simon; Carvajal, Garcia, Torres, Alba; Gavi, Busquets, Koke; Sarabia, Morata, Torres
