Nacional vs. Estoril (Saturday, 3.30pm)
Nacional will aim to build on their recent success when they host resurgent Estoril Praia for round 22 of the Primeira Liga on Saturday evening.
The hosts are coming off a 2-0 victory over Farense on Sunday, a result that saw them steer further clear of the danger zone, while the Canaries have surged up the standings to eighth after winning each of their last five matches.
We say: Nacional 1-2 Estoril Praia
While both sides come into this clash on a high after winning their previous matches, Estoril are favoured to prevail, given their blistering run of five consecutive victories.
> Primeira Liga preview: Nacional vs Estoril
Moreirense vs. Casa Pia (Saturday, 3.30pm)
Still searching for their first win in 2025, struggling Moreirense welcome Casa Pia to Parque Moreira for round 22 of the Primeira Liga.
The hosts are enduring a torrid run, winless in their last eight league matches and nine across all competitions, while the visitors have won three of their previous four encounters.
We say: Moreirense 0-1 Casa Pia
Moreirense have struggled in attack, failing to find the net in five of their last nine matches across all competitions, which could make it difficult for them to take anything from this game.
While the hosts may look to stay compact and grind out a result, their shaky defence could be exposed by Casa Pia's firepower, making an away win the likely outcome.
> Primeira Liga preview: Moreirense vs Casa Pia
Santa Clara vs. Benfica (Saturday, 6.00pm)
Fresh off a successful European outing, Benfica return to Primeira Liga action this weekend as they travel to Santa Clara for gameweek 22.
The Eagles secured a hard-fought 1-0 win at Monaco in midweek in the first leg of the Champions League knockout playoffs, while the hosts come into the match with more rest, having last played on Saturday.
We say: Santa Clara 2-3 Benfica
Both sides come into this encounter brimming with confidence after recent victories, but the away side hold the edge in terms of momentum, having strung together a longer winning run.
Santa Clara's strong home record makes them a formidable opponent, yet Benfica's dominance in this fixture suggests they will have the upper hand once again in what promises to be a high-scoring affair.
> Primeira Liga preview: Santa Clara vs Benfica
Sporting Lisbon vs. Arouca (Saturday, 8.30pm)
Fresh off a disappointing European outing, Sporting Lisbon return to Primeira Liga action as they welcome Arouca for round 22.
The Lions will look to bounce back from their humbling defeat at Estadio Jose Alvalade against German side Borussia Dortmund in the first leg of their Champions League knockout playoffs on Tuesday.
We say: Sporting Lisbon 3-1 Arouca
While both sides are enjoying strong league form, Sporting are expected to claim victory this weekend, given their formidable home record this season and their dominance in this fixture.
