Tottenham Hotspur welcome five-time winners Barcelona to Wembley Stadium on Wednesday night, aiming to put their first points on the board in this season's Champions League.
Two weeks on from a dramatic late loss at Inter Milan, the Lilywhites - now back in form after three wins in a row - have another chance to get their European campaign up and running.
Mauricio Pochettino has been pleased by the manner of his side's response since losing to Inter, but the ex-Espanyol player and manager has had to contend with a number of injury issues in the build-up to this game.
Here, Sports Mole looks at how Tottenham could line up for their opening Group B home match.
Tottenham have more injuries than any other Premier League side, with as many as eight players being ruled out for the visit of Barcelona.
Dele Alli is among those expected to miss out, but Pochettino delivered a positive update on the fitness of Christian Eriksen at the weekend and will likely include the Danish playmaker from the off if he has the chance.
There is more of a concern over skipper Hugo Lloris, who has now missed more than a month of action with a thigh injury, giving Michele Vorm - who has also since been struck down by injury - and Paulo Gazzaniga a chance to share goalkeeping duties.
Kieran Trippier and Danny Rose were used at wing-back in the 2-0 win at Huddersfield on Saturday, meanwhile, but Pochettino likes to rotate in that department so one or both of Serge Aurier and Ben Davies could return.
> Click here to see how Barcelona could line up for this fixture