Man City vs. Brighton (Wednesday, 6.00pm)
Both teams advanced to the fourth round of the FA Cup at the weekend, with Pep Guardiola's side cruising past Birmingham City, while Brighton knocked League Two side Newport County out on penalties.
We say: Manchester City 3-0 Brighton & Hove Albion
Manchester City have not been their usual dominant selves on the attacking front throughout the campaign, but at the other end of the pitch, their defensive prowess is evident. Brighton supporters will not be looking ahead to this tie with any optimism whatsoever, and this should be a routine win for Guardiola's men over the struggling Seagulls.
Our tipster partners are predicting over 2.5 goals.
Spurs vs. Fulham (Wednesday, 8.15pm)
Spurs have enjoyed a largely positive 12 months under Jose Mourinho, but they are without a win in four league matches and have slipped down the table.
Fulham are in need of points for a different reason as they enter this match inside the relegation zone, despite some improved performances.
We say: Tottenham Hotspur 2-0 Fulham
Tottenham are at risk of dropping out of the title picture if their winless run stretches on much longer.
A home meeting with a Fulham side in the relegation zone might just be the perfect fixture for Mourinho's men, even if the visitors have gone four without defeat.
Tottenham have won seven and drawn three of their last 11 final fixtures of a calendar year, and we can see them adding another win to that tally on Wednesday.
Our tipster partners are predicting under 3.5 goals.