Georginio Wijnaldum added to a Martin Skrtel own goal last weekend, so he continues in midfield alongside the oft-injured Siem de Jong, while Papiss Cisse continues to be preferred to Ayoze Perez up front.
Mauricio Pochettino put out a much-changed side for the 4-1 win over AS Monaco in the Europa League earlier this week, with only five of this afternoon's starting lineup having also started on Thursday.
Tottenham Hotspur: Lloris; Walker, Alderweireld, Vertonghen, Rose; Carroll, Dier, Lamela, Alli, Eriksen; Kane
Subs: Vorm, Davies, Trippier, Bentaleb, Chadli, Onomah, Son
Newcastle United: Elliot; Janmaat, Mbemba, Coloccini, Dummett; Sissoko, Anita, Colback, Wijnaldum, De Jong; Cisse
Subs: Darlow, Sterry, Mbabu, Gouffran, Thauvin, Perez, Mitrovic
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