Bournemouth midfielder David Brooks will miss Wales' Nations League game in Bulgaria on Wednesday due to injury.
Brooks, a second-half substitute in Sunday's goalless draw against the Republic of Ireland in Dublin, has withdrawn from the squad together with suspended pair Kieffer Moore and Joe Morrell.
Wales announced on Twitter: "Kieffer Moore and Joe Morrell have returned to their clubs with a one match suspension for accumulation of yellow cards. David Brooks has also left the camp after picking up an injury."
Brooks was a 77th-minute replacement for Daniel James in Dublin, but was not included in the squad for last weekend's friendly defeat to England.
He returned to full training with Bournemouth in February following two ankle operations, which forced him to miss most of the 2019-20 season.
Wales are currently top of Nations League Group B4 after winning two and drawing one of their first three games.